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| New research shows how psychedelic drug can help people with PTSD |
| MDMA, also known as Ecstasy, is known mainly as a club or street drug. But now it’s being touted as a medicine for people struggling with severe depression and PTSD. The FDA is designating it a “breakthrough therapy” after early trials. TODAY’s Savannah Guthrie spoke to two patients whose lives have been changed by the therapy. |
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| New COVID-19 treatment pill shows promising results amid battles over vaccine mandates |
| As a fierce battle erupts over newly announced vaccine mandates for private companies that impact tens of millions of workers, Pfizer is revealing promising results from a pill to treat COVID-19 and will seek emergency approval from the FDA. NBC’s Gabe Gutierrez reports for TODAY. |
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| Hoda and Jenna visit NYC's newest observation deck |
| TODAY's Hoda Kotb and Jenna Bush Hager arrive blindfolded at Summit One Vanderbilt, New York's newest observation deck at the fourth-tallest building in the city. They go inside bubble rooms, levitation sky boxes and exterior elevators. |
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| Ed Sheeran talks about his new music, fatherhood and more |
| Joining TODAY live from London, Ed Sheeran opens up about how marriage, new fatherhood and the death of a friend all went into the album, “=,” particularly the song “Visiting Hours.” He also reacts to video of himself doing an unsuccessful TV audition at 16 and gets a surprise from the woman who rejected him then. |
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| Try Joy Bauer's 2 standout Thanksgiving side dishes |
| TODAY nutritionist Joy Bauer is on the show making bacon-wrapped carrots and sweet potato mac and cheese. |
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| Shop winter accessories to keep you warm |
| 'Tis the season for wooly mittens and scarves. Lifestyle expert Amy E. Goodman shows TODAY winter accessories, beer blankets and more. |
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